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Article

The hypocretin/orexin system in health and disease.

Biological psychiatry - 15 Jul 2003

Nishino Seiji

Abstract excerpt

Using positional cloning in a canine model of narcolepsy and mouse gene knockouts, genes involved in the pathogenesis of narcolepsy in animals have been identified. Hypocretin/orexin ligand and hypocretin/orexin receptor genes are key to the pathogenesis of narcolepsy in animals. Mutations in hyp...

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Source

Identifiers

PMID: 12873797
DOI: 10.1016/s0006-3223(03)00349-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12873797-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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