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Article

Melatonin attenuates 17β-trenbolone induced insomnia-like phenotype and movement deficiency in zebrafish.

Chemosphere - 1 Aug 2020

Mi Ping, Gao Qian, Feng Ze-Yang, Zhang Jing-Wen, Zhao Xin, Chen Dong-Yan, Feng Xi-Zeng

Abstract excerpt

17β-trenbolone (17β-TBOH) is one of the dominant metabolites of trenbolone acetate, which is widely applied in beef cattle operations around the globe. The effects of environmental concentrations of 17β-trenbolone on the early development of zebrafish embryos have received very little attention. Melatonin could regulate sleep-wake cycle and plays a protective role in various adverse conditions. Here,...

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PMID: 32302915
DOI: 10.1016/j.chemosphere.2020.126762

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