Article
Methylenetetrahydrofolate reductase and angiotensin converting enzyme gene polymorphisms in two genetically and diagnostically distinct cohort of Alzheimer patients.
Neurobiology of aging - 1 Nov 2003
Seripa Davide, Forno Gloria Dal, Matera Maria G, Gravina Carolina, Margaglione Maurizio, Palermo Mark T, Wekstein David R, Antuono Piero, Davis Daron G, Daniele Antonio, Masullo Carlo, Bizzarro Alessandra, Gennarelli Massimo, Fazio Vito M
Abstract excerpt
The role of methylenetetrahydrofolate reductase (MTHFR) and angiotensin converting enzyme (ACE) gene polymorphisms as risk factors for the occurrence of Alzheimer's disease (AD) is still controversial. In this study, we investigated the common MTHFR C677-->T and ACE insertion/deletion (I/D) gene polymorphisms as risk factors for AD in two genetically and diagnostically distinct cohort of Alzheimer's patients. We...
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