Article

Rule of seven: a strategy for optimal propagation and innate immunity escape in human metapneumovirus

2026-05-08

Abstract excerpt

<title>Abstract</title> <p>Human metapneumovirus (hMPV) is a major cause of respiratory tract infections worldwide, particularly in pediatric and immunocompromised populations, yet no licensed vaccine is currently available. Here we report that during reverse genetic rescue of recombinant hMPV (rhMPV), a spontaneous adenosine insertion emerged at high frequency within a conserved adenosine hexamer in the viral G...

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Literature Corpus work: ea260144-d193-556a-af43-0dd8c7ace9d1
DOI: 10.21203/rs.3.rs-9262911/v1

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