Article
Changes in the cellular phenotype and extracellular matrix during progression of estrogen-induced mesenchymal kidney tumors in Syrian hamsters.
Virchows Archiv. B, Cell pathology including molecular pathology - 1 Jan 1991
Hacker H J, Vollmer G, Chiquet-Ehrismann R, Bannasch P, Liehr J G
Abstract excerpt
The cellular origin of estrogen-induced kidney tumors in male Syrian hamsters has been repeatedly the subject of controversy. Several authors have proposed that the tumors arise from proximal tubules, from a combination of tubular and interstitial stromal cells, or solely from interstitial cells. Because of the model character of this tumor for hormone-associated cancer, it was further investigated in this study...
Topics
- Adenylyl Cyclases
- Alkaline Phosphatase
- Animals
- Cell Adhesion Molecules, Neuronal
- Cricetinae
- Estradiol
- Extracellular Matrix Proteins
- Fibronectins
- Glucosephosphate Dehydrogenase
- Intermediate Filament Proteins