Article
Do studies in caveolin-knockouts teach us about physiology and pharmacology or instead, the ways mice compensate for 'lost proteins'?
British journal of pharmacology - 1 Feb 2007
Insel P A, Patel H H
Abstract excerpt
A wide array of phenotypic changes have been reported in mice with knockout of expression of caveolin-1. Neidhold et al. (2007) describe results in this issue that continue this trend by showing that saphenous arteries from adult caveolin-1 knockout mice lack caveolae, lose beta1-adrenoceptor-promoted relaxation, gain beta3-adrenoceptor-promoted relaxation but show no change in vasomotor response to...
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