Article
The key enzyme in galactose metabolism, UDP-galactose-4-epimerase, affects cell-wall integrity and morphology in Candida albicans even in the absence of galactose.
Fungal genetics and biology : FG & B - 1 Jun 2007
Singh Vijender, Satheesh Somisetty V, Raghavendra Mysore L, Sadhale Parag P
Abstract excerpt
The enzyme UDP-galactose-4-epimerase (GAL10) catalyzes a key step in galactose metabolism converting UDP-galactose to UDP-glucose which then can get metabolized through glycolysis and TCA cycle thus allowing the cell to use galactose as a carbon and energy source. As in many fungi, a functional h...
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