Article
KRE5 gene null mutant strains of Candida albicans are avirulent and have altered cell wall composition and hypha formation properties.
Eukaryotic cell - 1 Dec 2004
Herrero Ana B, Magnelli Paula, Mansour Michael K, Levitz Stuart M, Bussey Howard, Abeijon Claudia
Abstract excerpt
The UDP-glucose:glycoprotein glucosyltransferase (UGGT) is an endoplasmic reticulum sensor for quality control of glycoprotein folding. Saccharomyces cerevisiae is the only eukaryotic organism so far described lacking UGGT-mediated transient reglucosylation of N-linked oligosaccharides. The only gene in S. cerevisiae with similarity to those encoding UGGTs is KRE5. S. cerevisiae KRE5 deletion strains show...
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