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Article

Strain variation in Candida albicans glycolytic gene regulation.

mSphere - 21 Nov 2024

Kim Min-Ju, White Amelia M, Mitchell Aaron P

Abstract excerpt

Central carbon metabolism is vital for the proliferation of Candida albicans, a fungus that is prominent as a commensal and pathogen. Glycolytic genes are activated by overlapping activities of the transcription factors Tye7 and Gal4, as shown by studies in the SC5314 genetic background. However, regulatory relationships can vary among C. albicans isolates. Here, we analyzed Tye7- and Gal4-related phenotypes in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39431903
DOI: 10.1128/msphere.00579-24
PMCID: PMC11580466

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