Article
Recognition of Galactose by a Scaffold Protein Recruits a Transcriptional Activator for the <i>GAL</i> Regulon Induction in <i>Candida albicans</i>
2022-10-24
Abstract excerpt
The GAL pathway of yeasts has long served as a model system for understanding of how regulatory mode of eukaryotic metabolic pathways evolves. While Gal4 mode has been well-characterized in Saccharomycetaceae clade, little is known about the regulation of the GAL pathway in other yeasts. Here, we find that Rep1, a Ndt80-like family transcription factor, serves as a galactose sensor in the commensal-pathogenic fu...
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Identifiers and source
- Literature Corpus work
- f8268ab7-60c5-5b91-9a0b-bf52053ddd55
- DOI
- 10.1101/2022.10.24.513549
