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Article

Association between obsessive-compulsive disorder and a variable number of tandem repeats polymorphism in intron 2 of the serotonin transporter gene.

Progress in neuro-psychopharmacology & biological psychiatry - 30 Mar 2007

Baca-Garcia Enrique, Vaquero-Lorenzo Concepcion, Diaz-Hernandez Montserrat, Rodriguez-Salgado Beatriz, Dolengevich-Segal Helen, Arrojo-Romero Manuel, Botillo-Martin Carlota, Ceverino Antonio, Piqueras Jose Fernandez, Perez-Rodriguez M Mercedes, Saiz-Ruiz Jeronimo

Abstract excerpt

BACKGROUND: Pharmacological studies indicate a dysregulation of the serotonergic system in obsessive-compulsive disorder (OCD). A variable number tandem repeats (VNTR) polymorphism with three alleles (Stin2.9, Stin2.10, Stin2.12) has been described in intron 2 of the serotonin transporter (5-HTT) gene. This polymorphism has been associated with unipolar depression, bipolar disorder, schizophrenia, and anxiety...

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Source

Identifiers

PMID: 17174018
DOI: 10.1016/j.pnpbp.2006.10.016

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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