Article
Paraoxonase gene polymorphism and serum activity in progressive IgA nephropathy.
Journal of nephrology - 1 Jan 2000
Kovács Tibor J, Harris Shelley, Vas Tibor K, Seres Ildikó, Short Colin D, Wittmann István K, Paragh György, Mackness Michael I, Mackness Bharti, Durrington Paul N, Nagy Judit M, Brenchley Paul E C
Abstract excerpt
BACKGROUND: HDL-associated paraoxonase (PON1) reduces oxidation of lipids in LDL, and activity is inversely related to coronary heart disease risk with a beneficial effect on the development of atherosclerosis. Risk factors associated with atherosclerosis, such as hypertension, dyslipidemia and smoking, also promote the progression of chronic glomerulonephritides which may therefore be associated with...
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