Article
Paraoxnase1 Gene Polymorphism in Childhood Idiopathic Nephrotic Syndrome.
Nephron - 1 Jan 2016
Al-Eisa Amal A, Sukumaran Vazhappilly J, Haider Mohammad Z
Abstract excerpt
BACKGROUND: Paraoxonase1 (PON1) is a serum enzyme bound to high-density lipoproteins with antioxidant properties. Molecular studies of PON1 revealed 2 polymorphic sites at amino acids 55 and 192 resulting in 2 different allozymes, the L and M-genotype at residue 55 and A and B at site 192, respectively. We have studied the association between PON1 gene polymorphisms and the minimal change nephrotic syndrome/focal...
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