Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presence

1 Oct 2006

Abstract excerpt

Matrix metalloproteinases (MMPs) MMP-2, MMP-9, and MT1-MMP are required for basement membrane degradation in cervical carcinoma. We evaluated the expression and activity of MMPs and their inhibitors RECK and TIMP-2 in 3 human invasive cervical carcinoma cell lines. Two HPV16-positive cell lines (SiHa and CaSki) and an HPV-negative cell line (C33A) were cultured either onto a type-I collagen gel, Matrigel, or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Coagulation and Thrombosis Mechanisms
Share to Protease and Inhibitor Mechanisms
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17167534
DOI: 10.1139/o06-084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Higher expression and activity of metalloproteinases in human cervical carcinoma cell lines is associated with HPV presencePMID 17167534Read ↗

Human Papillomavirus Modulates Matrix Metalloproteinases During Carcinogenesis: Clinical Significance and Role of Viral OncoproteinsSemantic proximity Read ↗

MMP-9/RECK Imbalance: A Mechanism Associated with High-Grade Cervical Lesions and Genital Infection by Human Papillomavirus and Chlamydia trachomatis.Semantic proximity Read ↗

Expression of membrane type 1 matrix metalloproteinase in papillomavirus-positive cells: role of the human papillomavirus (HPV) 16 and HPV8 E7 gene productsSemantic proximity Read ↗

Proteases and HPV-Induced CarcinogenesisSemantic proximity Read ↗

Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma.Semantic proximity Read ↗

Polymorphism in the matrix metalloproteinase-2 gene promoter is associated with cervical neoplasm risk in Mexican women.Semantic proximity Read ↗

Differential expression of matrix metalloproteinases in activated c-ras-Ha-transfected immortalized human keratinocytes.Semantic proximity Read ↗

Tumor-associated serpin, squamous cell carcinoma antigen stimulates matrix metalloproteinase-9 production in cervical squamous cell carcinoma cell lines.Semantic proximity Read ↗

Frequent hypermethylation of 5' flanking region of TIMP-2 gene in cervical cancer.Semantic proximity Read ↗

Correlation between vascular endothelial growth factor-C expression and invasion phenotype in cervical carcinomas.Semantic proximity Read ↗

Membrane-type matrix metalloproteinase (MT-MMP) gene is expressed in stromal cells of human colon, breast, and head and neck carcinomas.Semantic proximity Read ↗

The E2 protein of human papillomavirus type 8 increases the expression of matrix metalloproteinase-9 in human keratinocytes and organotypic skin cultures.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.