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Proteases and HPV-Induced Carcinogenesis

21 Jun 2022

Abstract excerpt

Persistent infection with Human papillomavirus (HPV) is the main etiologic factor for pre-malignant and malignant cervical lesions. Moreover, HPV is also associated with oropharynx and other anogenital carcinomas. Cancer-causing HPV viruses classified as group 1 carcinogens include 12 HPV types, with HPV 16 and 18 being the most prevalent. High-risk HPVs express two oncoproteins, E6 and E7, the products of which...

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PMID: 35804810
DOI: 10.3390/cancers14133038

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