MMP-9/RECK Imbalance: A Mechanism Associated with High-Grade Cervical Lesions and Genital Infection by Human Papillomavirus and Chlamydia trachomatis.

doi:10.1158/1055-9965.EPI-15-0420

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Article

MMP-9/RECK Imbalance: A Mechanism Associated with High-Grade Cervical Lesions and Genital Infection by Human Papillomavirus and Chlamydia trachomatis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2015

Discacciati Michelle G, Gimenes Fabrícia, Pennacchi Paula C, Faião-Flores Fernanda, Zeferino Luiz C, Derchain Sophie M, Teixeira Júlio C, Costa Maria C, Zonta Marco, Termini Lara, Boccardo Enrique, Longatto-Filho Adhemar, Consolaro Marcia E L, Villa Luisa L, Maria-Engler Silvya S

Abstract excerpt

BACKGROUND: Matrix metalloproteinases (MMP) are important enzymes in the tumor microenvironment associated with progression of cervical intraepithelial neoplasia (CIN) toward squamous cell carcinoma (SCC) of the cervix. However, the role of MMPs in the inflammatory process associated with Chlamydia trachomatis infection concomitant with the carcinogenic process driven by HPV has not yet been addressed. In the...

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PMID: 26261088
DOI: 10.1158/1055-9965.EPI-15-0420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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