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Identification of Novel Fusion Genes in Testicular Germ Cell Tumors

9 Dec 2015

Abstract excerpt

Testicular germ cell tumors (TGCT) are the most frequently diagnosed solid tumors in young men ages 15 to 44 years. Embryonal carcinomas (EC) comprise a subset of TGCTs that exhibit pluripotent characteristics similar to embryonic stem (ES) cells, but the genetic drivers underlying malignant transformation of ECs are unknown. To elucidate the abnormal genetic events potentially contributing to TGCT malignancy,...

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PMID: 26659575
DOI: 10.1158/0008-5472.can-15-1790

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