Article
Tumor necrosis factor alpha promoter polymorphism associated with increased susceptibility to secondary hemophagocytic lymphohistiocytosis in the Korean population.
Cytokine - 1 Oct 2006
Chang Yoon Hwan, Lee Dong Soon, Jo Heui Seung, Cho Sung-Il, Yoon Hyung-Jin, Shin Sue, Yoon Jong-Hyun, Kim Ho Young, Hong Young Joon, Hong Seok Il, Cho Han Ik
Abstract excerpt
Secondary hemophagocytic lymphohistiocytosis (HLH) can be associated with various diseases including infections and lymphoma. The clinical findings of HLH can be explained by an increased production of cytokines such as tumor necrosis factor alpha (TNF-alpha). As not all the patients with infection or lymphoma have secondary HLH, we investigated the relationship between susceptibility to secondary HLH and...
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