NLRC4 Gene Single Nucleotide Polymorphisms Are Associated with the Prognosis of Hemophagocytic Lymphohistiocytosis.

doi:10.1155/2021/8581746

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NLRC4 Gene Single Nucleotide Polymorphisms Are Associated with the Prognosis of Hemophagocytic Lymphohistiocytosis.

Computational and mathematical methods in medicine - 1 Jan 2021

Li Yan, Sun Chengdong, Cui Liying, Wang Qiuying

Abstract excerpt

OBJECTIVE: To analyze and study the correlation between NLR family CARD domain-containing 4 (NLRC4) gene single nucleotide polymorphisms and the prognosis of patients with hemophagocytic lymphohistiocytosis (HLH). METHODS: In this study, we retrospectively studied the clinical data of 62 HLH patients, including 40 males and 22 females. The genomic DNA was extracted, and the genotypes at rs385076 locus and...

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PMID: 34925545
DOI: 10.1155/2021/8581746
PMCID: PMC8683185

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