Article
Exploration of a hypothesized independent association of a common 9p21.3 gene variant and ischemic stroke in patients with and without angiographic coronary artery disease.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2011
Plant Sheila R, Samsa Greg P, Shah Svati H, Goldstein Larry B
Abstract excerpt
BACKGROUND: Single-nucleotide polymorphisms (SNPs) at the chromosome 9p21.3 locus are associated with coronary artery disease (CAD). An association of this genomic region with ischemic stroke independent of its effect on CAD could suggest an additional, stroke-specific pathophysiological relationship. METHODS: Medical record review was used to identify 548 patients without a history of cerebrovascular disease and...
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