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Article

Comprehensive analysis of 22 XPC polymorphisms and bladder cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2006

Sak Sei Chung, Barrett Jennifer H, Paul Alan B, Bishop D Timothy, Kiltie Anne E

Abstract excerpt

Two major risk factors for bladder cancer are smoking and occupational exposure to chemicals. The XPC protein is crucial in the recognition and initiation of the nucleotide excision repair pathway which repairs the DNA adducts formed by carcinogens found in cigarette smoke and chemicals. Polymorphisms in the XPC gene have been shown to influence an individual's DNA repair capacity, and hence, increase that...

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Source

Identifiers

PMID: 17164382
DOI: 10.1158/1055-9965.EPI-06-0288

Genes

XPC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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