Article
Interactions between cigarette smoking and XPC-PAT genetic polymorphism enhance bladder cancer risk.
Oncology reports - 1 Jul 2012
Liu Yang, Wang Huanhuan, Lin Tianxin, Wei Quanfang, Zhi Yi, Yuan Fang, Song Bo, Yang Jin, Chen Zhiwen
Abstract excerpt
Inherited polymorphisms in the XPC gene that lead to a reduction in DNA repair capacity may increase susceptibility to bladder cancer. We investigated three polymorphisms of the XPC gene (PAT, Ala499Val and Lys939Gln) in 600 subjects with bladder cancer and in 609 healthy controls by a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)...
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