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Article

Detailed assessment of copy number alterations revealing homozygous deletions in 1p and 13q in mantle cell lymphoma.

Leukemia research - 1 Sept 2007

Flordal Thelander Emma, Ichimura Koichi, Collins V Peter, Walsh Sarah H, Barbany Gisela, Hagberg Anette, Laurell Anna, Rosenquist Richard, Larsson Catharina, Lagercrantz Svetlana

Abstract excerpt

Mantle cell lymphoma (MCL) is characterized by over-expression of cyclin Dl as a result of the characteristic t(11;14)(q13;q32). However, this translocation alone has proven not to be sufficient for lymphomagenesis, suggesting the involvement of additional alterations. We have characterized 35 cases of MCL by array comparative genomic hybridization with an average resolution of 0.97 Mb distributed over the...

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Share to Chromosomes, Human, Pair 1
Share to Chromosomes, Human, Pair 13

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cyclin-Dependent Kinase Inhibitor p18

Share to Genes, Tumor Suppressor

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Source

Identifiers

PMID: 17161458
DOI: 10.1016/j.leukres.2006.10.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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