Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma

doi:10.1002/(sici)1098-2264(199804)21:4<298::aid-gcc3>3.0.co;2-u

Article

Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma

1 Apr 1998

Abstract excerpt

We used comparative genomic hybridization (CGH) to screen for DNA copy number changes in 34 specimens from 27 cases of mantle cell lymphoma (MCL). The most common gains were detected at 3q (52%), 8q (30%), and 15q (26%), whereas the most frequent losses involved 13q (41%), 1p (33%), 6q (30%), 9p (30%), and 11q (30%). The gain of 3q, with a minimal common region at 3q26.1-27, appeared in more than half of the...

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