Article
Association of rs8066560 variant in the sterol regulatory element-binding protein 1 (SREBP-1) and miR-33b genes with hyperglycemia and insulin resistance.
Journal of pediatric endocrinology & metabolism : JPEM - 1 Jul 2014
Nikpour Parvaneh, Miranzadeh-Mahabadi Hajar, Emadi-Baygi Modjtaba, Kelishadi Roya
Abstract excerpt
OBJECTIVE: This study aims to evaluate the association of miR-33b/SREBP-1 rs8066560 with hyperglycemia and insulin resistance in Iranian children and adolescents. METHODS: This case-control study comprised 200 participants with 9-19 years of age, consisting of 100 MetS and 100 healthy controls. Anthropometric and biochemical parameters were measured, and the polymorphism was genotyped by TaqMan real-time PCR...
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