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Article

Association study of SREBF-2 gene polymorphisms and the risk of type 2 diabetes in a sample of Iranian population.

Gene - 20 Jun 2018

Galavi Hamidreza, Noorzehi Nafiseh, Saravani Ramin, Sargazi Saman, Mollashahee-Kohkan Fatemeh, Shahraki Hojat

Abstract excerpt

Type 2 diabetes mellitus (T2D) as an important metabolic disorder is accompanied by dysregulation in lipid metabolism. Sterol regulatory element-binding factor-2 (SREBF-2) gene has a substantive role in lipid metabolism. Recently published report indicated the overexpression of this gene in diabetic patients. So, in this preliminary study we evaluated the effects of three common single nucleotide polymorphisms...

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Identifiers

PMID: 29601949
DOI: 10.1016/j.gene.2018.03.080

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