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Article

Microsatellite markers within --SEA breakpoints for prenatal diagnosis of HbBarts hydrops fetalis.

Clinical chemistry - 1 Feb 2007

Ho Sherry Sze Yee, Chong Samuel S, Koay Evelyn S C, Chan Yiong Huak, Sukumar Ponnusamy, Chiu Lily-Lily, Wang Wen, Roy Ashim, Rauff Mary, Su Lin Lin, Biswas Arijit, Choolani Mahesh

Abstract excerpt

BACKGROUND: We sought to develop a rapid prenatal diagnostic test for simultaneous detection of HbBarts hydrops fetalis and exclusion of maternal contamination. METHODS: We developed a multiplex quantitative fluorescent PCR (QF-PCR) test that detects the presence/ absence of 2 microsatellite markers (16PTEL05/16PTEL06) located within breakpoints of the Southeast Asia ((-SEA)) deletion. HbBarts hydrops fetalis...

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Source

Identifiers

PMID: 17158194
DOI: 10.1373/clinchem.2006.075085

Genes

SEA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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