Article
Pax6 controls the proliferation rate of neuroepithelial progenitors from the mouse optic vesicle.
Developmental biology - 15 Jan 2007
Duparc Robert-Hugues, Abdouh Mohamed, David Jocelyn, Lépine Mireille, Tétreault Nicolas, Bernier Gilbert
Abstract excerpt
In vertebrates, a limited number of homeobox-containing transcription factors are expressed in the optic vesicle primordium and are required and sufficient for eye formation. At present, little is known about the distinct functions of these factors in optic vesicle growth and on the nature of the main neuroepithelial (NE) progenitor population present in this organ. We have characterized a multipotent cell...
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