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Article

Pax-6 is expressed early in the differentiation of a corneal epithelial model system.

Journal of cellular physiology - 1 Aug 2009

García-Villegas Refugio, Escamilla Juan, Sánchez-Guzmán Erika, Pastén Angela, Hernández-Quintero Miriam, Gómez-Flores Eber, Castro-Muñozledo Federico

Abstract excerpt

Pax-6 is a regulatory gene with a major role during visual system development, but its association with corneal epithelial differentiation is not clearly established. Using the RCE1-(5T5) cell line, which mimics corneal epithelial differentiation, we analyzed Pax-6 biological role. Immunostaining of proliferating colonies and confluent sheets showed that Pax-6-positive cells were also K3 keratin-positive,...

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Identifiers

PMID: 19347868
DOI: 10.1002/jcp.21771

Genes

RCE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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