Regulation by endogenous interferon of virus-induced cytokine gene expression in mouse macrophages.

doi:10.1159/000163652

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Article

Regulation by endogenous interferon of virus-induced cytokine gene expression in mouse macrophages.

Pathobiology : journal of immunopathology, molecular and cellular biology - 1 Jan 1991

Zawatzky R, Homfeld A

Abstract excerpt

In macrophages from inbred mice the magnitude of the interferon (IFN) response to Newcastle disease virus (NDV) infection is under genetic control of the locus If-1, with C57BL/6 carrying the 'high-producer' allele If-1h whereas BALB/c have the 'low-producer' allele If-1l. The IFN produced consis...

Topics

Alleles
Animals
Cells, Cultured
Cytokines
Gene Expression Regulation
Interferons
Interleukin-6
Macrophage Colony-Stimulating Factor
Macrophages
Mice
Newcastle disease virus

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