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Article

IL-2 induces expression and secretion of IFN-gamma in murine peritoneal macrophages.

Journal of leukocyte biology - 1 Sept 2005

Puddu Patrizia, Carollo Maria, Pietraforte Immacolata, Spadaro Francesca, Tombesi Marina, Ramoni Carlo, Belardelli Filippo, Gessani Sandra

Abstract excerpt

We investigated the effect of interleukin (IL)-2, a T cell growth factor capable of activating certain macrophage functions, on interferon (IFN)-gamma expression in resting mouse peritoneal macrophages (PM). IL-2 addition to PM from different mouse strains up-modulated IFN-gamma mRNA and protein secretion. It is notable that endogenous type I and II IFNs did not play any role in the IL-2-mediated effect, as...

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Identifiers

PMID: 15951352
DOI: 10.1189/jlb.0105035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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