Downregulation of Newcastle disease virus (NDV)-dependent IFN-alpha/beta production in macrophages by IFN-induced gene products of the locus If-1.

doi:10.1016/0923-2494(92)80080-5

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Article

Downregulation of Newcastle disease virus (NDV)-dependent IFN-alpha/beta production in macrophages by IFN-induced gene products of the locus If-1.

Research in immunology - 1 Jan 1992

Zawatzky R, Wurmbaeck H

Abstract excerpt

We have found that in cultured mouse bone-marrow-derived macrophages (BMDM), endogenous IFN-beta specifically regulates Newcastle disease virus (NDV) induced interferon (IFN)-alpha/beta synthesis, possibly by influencing the activity of genes within the regulatory locus If-1. Comparison of anti-I...

Topics

Alleles
Animals
Cells, Cultured
Down-Regulation
Gene Expression Regulation
Genes, Regulator
Interferon-alpha
Interferon-beta
Macrophages
Newcastle Disease
Newcastle disease virus

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