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Article

Differential expression of epidermal growth factor-related proteins in human colorectal tumors.

1 Sept 1991

Abstract excerpt

Amphiregulin (AR) and cripto are proteins that are structurally related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). AR is also functionally related to this family of growth regulatory molecules and is able to bind and activate the 170-kDa EGF receptor (EGFR). Human EGFR-3 (HER3)/ERBB3 is a recently identified protein related to the EGFR that is widely expressed in breast...

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PMID: 1715580
DOI: 10.1073/pnas.88.17.7792

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