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Article

Downregulation of epidermal growth factor receptor family receptors and ligands in a mutant K-ras group of patients with colorectal cancer.

Molecular medicine reports - 1 Apr 2016

Nagaoka Tomoko, Kitaura Kazutaka, Miyata Yukinaga, Kumagai Kenichi, Kaneda Goro, Kanazawa Hideki, Suzuki Satsuki, Hamada Yoshiki, Suzuki Ryuji

Abstract excerpt

The present study investigated the expression profiles of the epidermal growth factor receptor (EGFR) family, which consists of four transmembrane tyrosine kinase receptors and their eight ligands, in 122 patients with colorectal cancer (CRC) using reverse transcription-quantitative polymerase chain reaction analysis. On comparison of the CRC primary tumor and matched adjacent normal mucosa (ANM) tissue samples,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26935861
DOI: 10.3892/mmr.2016.4951

Genes

AREG
BTC
EGF
EGFR
EREG
NRG1
AMN
NRG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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