Article
Two nonallelic insulin genes in Xenopus laevis are expressed differentially during neurulation in prepancreatic embryos.
Proceedings of the National Academy of Sciences of the United States of America - 1 Sept 1991
Shuldiner A R, de Pablo F, Moore C A, Roth J
Abstract excerpt
Insulin, traditionally regarded as a metabolic hormone, also can potently stimulate growth and differentiation in many cell types. To study further the potential role of insulin during early embryogenesis, we have used the amphibian Xenopus laevis, a versatile model of vertebrate development. Using (i) nucleotide sequences of two previously cloned cDNAs that correspond to two different nonallelic Xenopus insulin...
Topics
- Alleles
- Animals
- Base Sequence
- Embryo, Nonmammalian
- Female
- Gene Expression
- Genes
- Insulin
- Male
- Molecular Sequence Data
- Oligonucleotide Probes