Evidence that Xenopus laevis contains two different nonallelic insulin-like growth factor-I genes.

doi:10.1016/0006-291x(90)91934-k

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Article

Evidence that Xenopus laevis contains two different nonallelic insulin-like growth factor-I genes.

Biochemical and biophysical research communications - 15 Jan 1990

Shuldiner A R, Nirula A, Scott L A, Roth J

Abstract excerpt

Using the polymerase chain reaction (PCR), we have amplified and characterized partial nucleotide sequences of two distinct insulin-like growth factor-I genes (designated IGF-I' and IGF-I") from the amphibian, Xenopus laevis. The amplified fragments encoded much of the coding region of the mature peptide (exon III in mammalian IGF-I genes), and exhibited 93% similarity to each other, and 68-82% similarity to...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Blotting, Southern
DNA
Genes
Homozygote
Humans
Insulin-Like Growth Factor I
Liver
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multigene Family

Oligonucleotide Probes

Polymerase Chain Reaction

Sequence Homology, Nucleic Acid

Somatomedins

Xenopus laevis

Source

Open in PubMed

Identifiers

PMID: 2302204
DOI: 10.1016/0006-291x(90)91934-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2302204-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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