Article
Genetic intra-tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours.
The Journal of pathology - 1 Feb 2007
Khalique L, Ayhan A, Weale M E, Jacobs I J, Ramus S J, Gayther S A
Abstract excerpt
Genetic analysis of solid tumours using DNA or cDNA expression microarrays may enable individualized treatment based on the profiles of genetic changes that are identified from each patient. This could result in better response to adjuvant chemotherapy and, consequently, improved clinical outcome. So far, most research studies that have tested the efficacy of such an approach have sampled only single areas of...
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