Article
A sharper instrument for dissecting signalling events: a specific AGC kinase inhibitor.
The Biochemical journal - 1 Jan 2007
Proud Christopher G
Abstract excerpt
Small-molecule inhibitors are now widely used to try to dissect regulatory signalling events. Many of these interfere with the function of protein kinases, often as part of signalling cascades. In addition to their utility as tools for the researcher, the long-term aspiration is that certain of these compounds may be useful as therapeutic agents for the treatment of conditions that arise from the dysregulation of...
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