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Article

Gene rearrangement and comparative genomic hybridization studies of classic Hodgkin lymphoma expressing T-cell antigens.

Archives of pathology & laboratory medicine - 1 Dec 2006

Aguilera Nadine S I, Chen Jian, Bijwaard Karen E, Director-Myska Alison E, Barekman Carol L, Millward Carl, Lichy Jack, Abbondanzo Susan L

Abstract excerpt

CONTEXT: Reed-Sternberg cells in classic Hodgkin lymphoma are enigmatic and difficult to study because they are so sparse. Tissue microdissection allows for the isolation of single Reed-Sternberg cells. Isolated Reed-Sternberg cells show clonal immunoglobulin gene rearrangement indicating a B-cell origin. Rarely, Reed-Sternberg cells in classic Hodgkin lymphoma express T-cell antigens, suggesting a possible...

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Identifiers

PMID: 17149949
DOI: 10.5858/2006-130-1772-GRACGH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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