Article
Gene rearrangements and T-cell lymphomas.
Archives of dermatology - 1 Nov 1993
Terhune M H, Cooper K D
Abstract excerpt
BACKGROUND: Cutaneous T-cell lymphomas comprise a broad spectrum of neoplasia ranging from indolent to highly aggressive types. To determine subset lineage and malignant vs benign nature, morphologic analysis, immunophenotyping, and flow cytometry have been used. However, given the shortcomings of these methods, molecular genetic techniques, which take particular advantage of the clonal nature of malignancy, are...
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