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Article

Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2

15 Feb 2002

Abstract excerpt

Hodgkin- and Reed-Sternberg (HRS) cells microdissected from 41 classical Hodgkin lymphomas (cHL) of 40 patients comprising 8 lymphocyte-rich (cHL-LR), 16 nodular sclerosis (cHL-NS), 15 mixed-cellularity (cHL-MC), and 2 lymphocyte-depletion (cHL-LD) subtypes were analyzed by comparative genomic hybridization for recurrently imbalanced chromosomal subregions. Chromosomal gains most frequently involved chromosome 2p...

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PMID: 11830490
DOI: 10.1182/blood.v99.4.1381

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