Study on gene diagnosis of haemophilia A.

doi:10.1007/BF02887925

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Article

Study on gene diagnosis of haemophilia A.

Journal of Tongji Medical University = Tong ji yi ke da xue xue bao - 1 Jan 1993

Liu X X, Guo S, Zhong N

Abstract excerpt

We have successfully diagnosed 24 individuals of 5 haemophilia A pedigrees with RFLP linkage analysis and gene amplification in vitro (PCR) technique. Detecting with the I14-E18, we found the carriers of family A and B were not heterozygotes of Bcl I RFLP. They were homozygotes of 3.0 kb/3.0 kb a...

Topics

Base Sequence
DNA
Factor VIII
Female
Fetal Diseases
Genotype
Hemophilia A
Heterozygote
Humans
Male
Molecular Sequence Data
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Pregnancy
Prenatal Diagnosis

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