Article
Association of genetic variants, ethnicity and preterm birth with amniotic fluid cytokine concentrations.
Annals of human genetics - 1 Mar 2010
Menon Ramkumar, Fortunato Stephen J, Edwards Digna R Velez, Williams Scott M
Abstract excerpt
We examined the association of 166 single nucleotide polymorphisms (SNPs) in cytokines and cytokine related genes with cytokine concentrations (IL-1beta, IL-8, and IL-10) in the amniotic fluid (AF). These cytokines have been associated with spontaneous preterm birth (PTB) and their genetic regulation may play a role in disease risk. These associations were studied in both PTB and term births in African Americans...
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