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Maternal-fetal proinflammatory cytokine gene polymorphism and preterm birth.

DNA and cell biology - 1 Jan 2012

Yılmaz Yaprak, Verdi Hasibe, Taneri Ayşe, Yazıcı Ayse Canan, Ecevit Ayşe Nur, Karakaş Nazmi Mutlu, Tarcan Aylin, Haberal Ali, Ozbek Namık, Atac Fatma Belgin

Abstract excerpt

Association between maternal-fetal proinflammatory cytokine genotype and preterm birth was studied. Isolated genomic DNA from maternal and cord blood samples of 100 preterm and 101 term labors were used for TNFα (-238G/A, -308G/A), IL-1α (4845G/T), and IL-1β (-511C/T) genotyping. TNFα -238 GA genotype in term neonates was significantly higher than the premature neonates (p<0.05). Maternal-fetal TNFα -238...

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Identifiers

PMID: 21682548
DOI: 10.1089/dna.2010.1169

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