Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Spemann organizer gene, <i>Goosecoid</i> , promotes tumor metastasis

1 Dec 2006

Abstract excerpt

The process of invasion and metastasis during tumor progression is often reminiscent of cell migration events occurring during embryonic development. We hypothesized that genes controlling cellular changes in the Spemann organizer at gastrulation might be reactivated in tumors. The Goosecoid homeobox transcription factor is a known executer of cell migration from the Spemann organizer. We found that indeed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Hippo pathway signaling and YAP/TAZ
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17142318
DOI: 10.1073/pnas.0608636103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Spemann organizer gene, <i>Goosecoid</i> , promotes tumor metastasisPMID 17142318Read ↗

Mesenchyme Forkhead 1 ( <i>FOXC2</i> ) plays a key role in metastasis and is associated with aggressive basal-like breast cancersSemantic proximity Read ↗

SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patientsSemantic proximity Read ↗

Architectural Transcription Factor HMGI(Y) Promotes Tumor Progression and Mesenchymal Transition of Human Epithelial CellsSemantic proximity Read ↗

Human Schlafen 5 regulates reversible epithelial and mesenchymal transitions in breast cancer by suppression of ZEB1 transcriptionSemantic proximity Read ↗

Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives.Semantic proximity Read ↗

Homeobox genes: potential candidates for the transcriptional control of the transformed and invasive phenotype.Semantic proximity Read ↗

A <i>Drosophila</i> RNAi screen reveals conserved glioblastoma-related adhesion genes that regulate collective cell migrationSemantic proximity Read ↗

A role for CBFβ in maintaining the metastatic phenotype of breast cancer cells.Semantic proximity Read ↗

GATA3 in development and cancer differentiation: Cells GATA have it!Semantic proximity Read ↗

FOXF2 reprograms breast cancer cells into bone metastasis seedsSemantic proximity Read ↗

<i>HOXB7</i> induces STAT3-mediated transformation and lung metastasis in immortalized mammary gland NMuMG cellsSemantic proximity Read ↗

The <i>C. elegans</i> homolog of the <i>Evi1</i> proto-oncogene, <i>egl-43</i> , coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.