Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of E-cadherin-dependent and -independent events in a new model of c-Fos-mediated epithelial-mesenchymal transition.

Experimental cell research - 15 Jan 2007

Mejlvang Jakob, Kriajevska Marina, Berditchevski Fedor, Bronstein Igor, Lukanidin Eugene M, Pringle J Howard, Mellon J Kilian, Tulchinsky Eugene M

Abstract excerpt

Fos proteins have been implicated in control of tumorigenesis-related genetic programs including invasion, angiogenesis, cell proliferation and apoptosis. In this study, we demonstrate that c-Fos is able to induce mesenchymal transition in murine tumorigenic epithelial cell lines. Expression of c-Fos in MT1TC1 cells led to prominent alterations in cell morphology, increased expression of mesenchymal markers,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta Catenin
Share to Cadherins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Adhesion

Share to Epithelial Cells

Share to Extracellular Matrix

Share to Mesoderm

Share to Neoplasm Invasiveness

Share to Proto-Oncogene Proteins c-fos

Source

Identifiers

PMID: 17141758
DOI: 10.1016/j.yexcr.2006.10.017

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of E-cadherin-dependent and -independent events in a new model of c-Fos-mediated epithelial-mesenchymal transition.PMID 17141758Read ↗

beta-Catenin and TGFbeta signalling cooperate to maintain a mesenchymal phenotype after FosER-induced epithelial to mesenchymal transition.Semantic proximity Read ↗

Epithelial-Mesenchymal Transitions in Cancer ProgressionSemantic proximity Read ↗

Immediate and delayed effects of E-cadherin inhibition on gene regulation and cell motility in human epidermoid carcinoma cells.Semantic proximity Read ↗

Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion.Semantic proximity Read ↗

CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo.Semantic proximity Read ↗

c-Fos induces chondrogenic tumor formation in immortalized human mesenchymal progenitor cellsSemantic proximity Read ↗

Expression of c-ets-1 mRNA is associated with an invasive, EMT-derived phenotype in breast carcinoma cell lines.Semantic proximity Read ↗

<i>Foxc1</i> controls cell fate decisions during transforming growth factor β induced epithelial to mesenchymal transition through the regulation of fibroblast growth factor receptor 1 expressionSemantic proximity Read ↗

Osteoblasts are target cells for transformation in c-fos transgenic mice.Semantic proximity Read ↗

The proto-oncoprotein c-Fos negatively regulates hepatocellular tumorigenesis.Semantic proximity Read ↗

Transcriptional inhibition of matrix metalloproteinase 9 (MMP-9) activity by a c-fos/estrogen receptor fusion protein is mediated by the proximal AP-1 site of the MMP-9 promoter and correlates with reduced tumor cell invasion.Semantic proximity Read ↗

The PDZ domains of zonula occludens-1 induce an epithelial to mesenchymal transition of Madin-Darby canine kidney I cells. Evidence for a role of beta-catenin/Tcf/Lef signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.