Article
Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects.
Schizophrenia research - 1 Dec 2006
Passos Gregorio Sheila, Gattaz Wagner F, Tavares Hildeberto, Kieling Christian, Timm Sally, Wang August G, Berg Rasmussen Henrik, Werge Thomas, Dias-Neto Emmanuel
Abstract excerpt
Abnormality in neurodevelopment is one of the most robust hypotheses on the etiology of schizophrenia and has found substantial support from brain imaging and genetic studies. Neurodevelopmental processes involve several signaling pathways, including the Notch, but little is known at present rega...
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