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Article

The balance between heritable and environmental aetiology of human disease.

Nature reviews. Genetics - 1 Dec 2006

Hemminki Kari, Lorenzo Bermejo Justo, Försti Asta

Abstract excerpt

The Human Genome Project and the ensuing International HapMap Project were largely motivated by human health issues. But the distance from a DNA sequence variation to a novel disease gene is considerable; for complex diseases, closing this gap hinges on the premise that they arise mainly from heritable causes. Using cancer as an example of complex disease, we examine the scientific evidence for the hypothesis...

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Identifiers

PMID: 17139327
DOI: 10.1038/nrg2009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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