An integrated epigenetic and genetic approach to common human disease.

doi:10.1016/j.tig.2004.06.009

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Article

An integrated epigenetic and genetic approach to common human disease.

Trends in genetics : TIG - 1 Aug 2004

Bjornsson Hans T, Fallin M Daniele, Feinberg Andrew P

Abstract excerpt

Epigenetic information is heritable during cell division but is not contained within the DNA sequence itself. Despite increasing evidence for and interest in the role of epigenetics in human disease, particularly in cancer, virtually no epigenetic information is routinely or systematically measured at the genome level. The current population-based approach to common disease relates common DNA sequence variants to...

Topics

Epigenesis, Genetic
Evolution, Molecular
Genetic Variation
Genome
Humans
Models, Genetic
Phenotype

Source

Open in PubMed

Identifiers

PMID: 15262407
DOI: 10.1016/j.tig.2004.06.009

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