No association of type 1 diabetes with a functional polymorphism of the LRAP gene.

doi:10.1016/j.molimm.2006.10.015

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Article

No association of type 1 diabetes with a functional polymorphism of the LRAP gene.

Molecular immunology - 1 Mar 2007

Qu Hui-Qi, Marchand Luc, Fréchette Rosalie, Bacot François, Lu Yang, Polychronakos Constantin

Abstract excerpt

AIMS/HYPOTHESIS: In a recent linkage analysis of genome-wide gene-expression patterns in lymphoblastoid lines, the gene encoding the leukocyte-derived arginine aminopeptidase (LRAP) was identified as having its expression levels modulated by one of the most pronounced effects in cis, mapping to a single-nucleotide polymorphism (rs2762). As this enzyme has an important role in processing antigenic peptides for the...

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PMID: 17129607
DOI: 10.1016/j.molimm.2006.10.015

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